The Gunners currently hold a four-point lead over second-placed Manchester City and will look to capitalize on a fixture rearranged from next month's Carabao Cup final weekend. For Wolves, the season has been historically difficult as they sit rooted to the foot of the table with just nine points from 26 matches.
In team news, Hwang Hee-chan and Toti Gomes are ruled out for Wolves, while Arsenal will be missing captain Martin Ødegaard and Kai Havertz but both are "very hopeful" to return for Sunday's North London derby. The reverse fixture in December saw Arsenal edge past Wolves 2-1 thanks to a 94th-minute own goal.