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Relegation-threatened West Ham travel to Liverpool in search of what would be only their fourth top-flight win at Anfield.
When scrapping in a relegation battle, Anfield is arguably the last ground West Ham would want to visit to try to pick-up some much-needed points.
The Hammers have won just three of their 63 top-flight visits to Liverpool and only one of those – in August 2015 – has come since 1963.
Encompassing home games, their overall record against the Reds is also poor, with a solitary victory in their past 19 encounters.
At least boss Nuno Espirito Santo has a win at Anfield on his CV having masterminded his then Nottingham Forest side to their first win at Liverpool in any competition since 1969 with a 1-0 top-flight victory last season.
However, the eight defeats the Portuguese has suffered in the Premier League against the Reds is his most against any side.
At least the Hammers come into this match in form. The 11 points they have accrued over their past six league games is as many as they had mustered from their previous 18.
They were left extremely frustrated by their goalless draw with Bournemouth last Saturday, during which they had 20 shots and an xG of 3.27 that was comfortably the highest by a Premier League side not to score in a game this season.
They did, though, find comfort at the other end of the pitch as they recorded a second clean sheet in three matches, equalling their tally across their previous 35 league games.
Liverpool increase unbeaten run but not hitting top form
Liverpool extended their run to just two defeats in 20 matches with a victory at Nottingham Forest last weekend, but they were again unconvincing.
The Reds had to rely on a Premier League record-extending 48th winning goal in the 90th minute or later to secure the three points that keeps them in the mix for a Champions League spot.
It was their third injury-time winner this season - the most of any side - and only one short of their record for a Premier League campaign set in 2008-09.
However, given Arne Slot's struggles with the club's injury list, players losing form and an increasingly restless fanbase, a win is a win.
After back-to-back 1-0 victories, they are now targeting three wins without conceding for the first time since Slot's first three games in charge of the club.
Following their Anfield defeat by Forest, who were 19th in the table at the time, in November, the Reds will be desperate to avoid losing two Premier League home games in a season against sides starting the day in the relegation zone for the first time since 1992-93.
One further statistical quirk involving these sides: Liverpool have scored the lowest share of their goals in the opening 45 minutes of top-flight games this season - just 31% (13 of 42) - while West Ham have scored a Premier League high 59% of theirs in the second half of games (19 of 32).