The Dutch international suffered the injury during training ahead of Barcelona's La Liga match against Villarreal. Initial tests suggest a possible muscle tear, which would keep him sidelined for up to four weeks.
De Jong's absence is particularly frustrating for Hansi Flick, who had just regained a nearly full squad. With Pedri having recently returned, the Dutchman's injury leaves a significant gap in midfield that may be filled by Marc Bernal, Marc Casado, or Eric García.